TOP 10 Things to do in Siena, Italy! Siena, Italy is an amazing place to visit in Italy. If you want to know top 10 what to do in Siena or you need a travel guide, please keep watching. For wine enthusiasts, Enoteca Italiana is a must-visit destination. Located in the impressive Medici Fortress, it offers tastings of the finest Tuscan wines, including the world-renowned Chianti. Nothing defines Siena more than the Palio, a thrilling horse race that takes place in Piazza del Campo each July and August. The event is not just a race but a celebration of centuries-old traditions, with parades, flag-throwing, and intense rivalries between the contrade. Watching the horses thunder around the square while the crowd roars is an unforgettable experience.